Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredient (API)
USP / BP / EP (as applicable)
Abacavir Sulfate
C₁₄H₁₈N₆O • H₂SO₄
≈ 368.4 g/mol
188062-50-2
(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl methanol sulfate
Carbocyclic nucleoside analogue
Antiretroviral
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Soluble in water; slightly soluble in methanol |
| Melting Point | ~165–175°C (decomposes) |
| pH | 5.0 – 6.0 |
Abacavir Sulfate is a synthetic carbocyclic nucleoside analogue widely used as an antiretroviral agent for the management of HIV-1 infection. It is a key component of fixed-dose combination therapies for adult and pediatric patients.
Abacavir is converted intracellularly into its active metabolite, carbovir triphosphate, which competitively inhibits HIV reverse transcriptase. By integrating into the viral DNA chain, it causes premature chain termination, thereby halting further synthesis of viral DNA. Through this mechanism, Abacavir effectively suppresses viral replication and helps reduce the overall viral load, particularly when used as part of a combination antiretroviral therapy (ART) regimen.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Yes, an open part can be shared upon request for regulated markets.
Yes, region-specific regulatory documents and CTD Sections 2 & 3 can be provided.
Yes, Abacavir is widely used in pediatric oral solutions and tablets.
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Any patented products are excluded from our offerings in regions where such patents are currently in force.