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Bisoprolol Fumarate Structure

PRODUCT TYPE

Active Pharmaceutical Ingredient (API)

GRADE

BP / USP (as applicable)

CHEMICAL FORMULA

C18H31NO4

IUPAC NAME

(±)-1-[4-(2-isopropoxyethoxy)phenyl]-3-[(propan-2-yl)amino]propan-2-ol fumarate

CAS NUMBER

66722-44-9

MOLECULAR WEIGHT

325.43 g/mol (Bisoprolol base), 408.49 g/mol (as fumarate)

CHEMICAL CLASS

Beta-1 selective adrenergic receptor blocker (β1-blocker)

THERAPEUTIC CLASS

Antihypertensive / Cardiovascular agent

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to off white crystalline solid
Solubility Soluble in water; slightly soluble in alcohol
Melting Point 102–108 °C
pH ~4–5

Product Description

Bisoprolol Fumarate is a selective β1-adrenergic receptor blocker widely used in the management of cardiovascular diseases. It is effective in controlling hypertension, treating angina (chest pain), and supporting heart failure therapy. As a high-quality pharmaceutical API, it is manufactured under strict WHO-GMP, USFDA, and BP/USP standards, making it suitable for global supply to pharmaceutical manufacturers.

How Bisoprolol Fumarate Works

Bisoprolol selectively blocks β1-adrenergic receptors in the heart. It reduces heart rate, cardiac output, and myocardial oxygen demand. It lowers blood pressure and helps manage angina and heart failure.

Use(s)

Adverse Effects

Why choose Salius for Bisoprolol Fumarate?

  1. Regulatory-Grade Manufacturing Standards
    They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release.
  2. Enhancing Cost-Effectiveness Through Large Volume API Utilization
    As an exporter and distributor house, Salius aims to deliver high-quality APIs at competitive prices, a key advantage for cost-sensitive markets.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.
  4. Documents We Provide
  5. Transparency & Trustworthiness
    They present as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

Bisoprolol primarily targets β1-adrenergic receptors, which are mostly located in the heart. This selective action helps reduce heart rate, cardiac output, and blood pressure. However, at higher doses, Bisoprolol may lose some selectivity and affect β2 receptors found in the lungs and blood vessels.

No, Bisoprolol is not addictive, and it does not produce euphoria or dependence. Abrupt discontinuation may lead to rebound high blood pressure, increased heart rate, or worsening chest pain (angina).

Weight gain is not a common side effect, but a small number of patients may experience mild weight changes. This is usually linked to reduced metabolism due to beta-blocker therapy, mild fluid retention, or lower physical activity caused by fatigue (rare).

Better stability during storage and transport, improved solubility helping in uniform tablet formulation, enhanced bioavailability ensuring consistent therapeutic effect, and reduced degradation, especially under humid conditions. In pharmaceutical manufacturing, salts like fumarate are often chosen to achieve optimal processing, longer shelf life, and reliable performance in finished dosage forms.

Yes. Bisoprolol Fumarate requires controlled storage conditions to maintain potency and stability. Keep in a dry, airtight container, protect from light, moisture, and heat, and avoid long exposure to open air due to hygroscopic tendencies.

Place an Order or Request a Quote from Salius Pharma

Looking to source Bisoprolol Fumarate or other high-quality pharmaceutical products?
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Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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