Chlorthalidone

Synonyms

• Chlortalidone, Chlorthalidon, 2-Chloro-5-sulfamylbenzoyl-1,2-dihydro-3H-isoindol-1-one

PHYSIOCHEMICAL PROPERTIES

Product Description

Chlorthalidone is a thiazide-like diuretic, structurally different from thiazides but providing a longer duration of action, making it one of the most effective drugs for chronic hypertension. It is widely used in monotherapy and fixed-dose combinations (FDCs) with ACE inhibitors, ARBs, beta-blockers, and potassium-sparing diuretics.

How Chlorthalidone Works

Chlorthalidone works primarily in the distal convoluted tubule by: • Inhibiting Na⁺/Cl⁻ symporter, reducing sodium and chloride reabsorption. • Increased urinary excretion of Na⁺, Cl⁻, water → diuresis. • Reduces plasma volume → lower cardiac output → antihypertensive effect.

Use(s)

• Hypertension
• Edema associated with congestive heart failure
• Kidney disorders
• Prevention of calcium kidney stones

Adverse Effects

• Hypokalemia
• Increased urination
• Dizziness
• Hyperuricemia

Why choose Salius for Chlorthalidone?

1. Regulatory-Grade Manufacturing Standards
   They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release.
2. Enhancing Cost-Effectiveness Through Large Volume API Utilization
   As an exporter and distributor house, Salius aims to deliver high-quality APIs at competitive prices, a key advantage for cost-sensitive markets.
3. Global Export Experience & Documentation Support
   Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.

4. Transparency & Trustworthiness
   They present as a government-recognized star export house with strong quality and delivery ratings.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Chlorthalidone
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.