Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredient (API)
C₂₁H₂₅ClO₆ · C₃H₈O₂ · H₂O (for monohydrate with propanediol)
approx. 476.55 g/mol (monohydrate + propanediol)
461432-26-8
(2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol propanediol monohydrate
SGLT2 (Sodium-Glucose Cotransporter-2) Inhibitor
Antidiabetic agent (for Type 2 Diabetes Mellitus); also used in heart failure & CKD management
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Freely soluble in methanol; soluble in ethanol; sparingly soluble in water |
| Melting Point | 70–75°C |
| pH | - |
Dapagliflozin Propaneadiol is the stable hydrate form of Dapagliflozin, an innovative SGLT2 inhibitor used in the management of Type 2 diabetes mellitus, heart failure, and chronic kidney disease. The propanediol monohydrate form is preferred in API manufacturing due to its improved crystallinity, stability, and handling characteristics.
Dapagliflozin selectively inhibits the SGLT2 transporter in the proximal renal tubules.
Action Steps:
Blocks SGLT2 protein responsible for ~90% renal glucose reabsorption
Leads to increased urinary glucose excretion (UGE)
Reduces fasting and post-prandial glucose levels
Improves insulin sensitivity and reduces glucotoxicity
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
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