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Diacerein Structure

Product Type

Active Pharmaceutical Ingredient (API)

Molecular Formula

C₁₉H₁₀O₇

Molecular Weight

368.28 g/mol

CAS Number

138-54-7

IUPAC Name

4,5-diacetyloxy-9,10-dioxo-anthracene-2-carboxylic acid

Chemical Class

Anthraquinone derivative

Therapeutic Class

Symptomatic slow-acting drug for osteoarthritis (SYSADOA); chondroprotective agent

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance Yellow to orange crystalline powder
Solubility Slightly soluble in water; soluble in ethanol, acetone
Melting Point 252–256°C
pH 4–5

Product Description

Diacerein is a slow-acting symptomatic drug for osteoarthritis (SYSADOA) with anti-inflammatory and chondroprotective properties. It is primarily used to:
• Reduce joint pain and stiffness in osteoarthritis
• Protect cartilage from degradation
It is considered an alternative to NSAIDs for long-term management, especially when avoiding gastrointestinal side effects.

How Diacerein Works

Primary Action: Inhibits interleukin-1β (IL-1β) activity, a major mediator in cartilage degradation.
Reduces matrix metalloproteinases (MMPs), which break down cartilage extracellular matrix.
Exhibits anti-inflammatory effects by reducing pro-inflammatory cytokines in synovial fluid.
Stimulates synthesis of proteoglycans and collagen in cartilage.

Use(s)

Adverse Effects

Why choose Salius for Diacerein?

  1. Regulatory-Grade Manufacturing Standards
    They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release
  2. Enhancing Cost-Effectiveness Through Large Volume API Utilization
    As an exporter and distributor house, Salius aims to deliver high-quality APIs at competitive prices, a key advantage for cost-sensitive markets.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.
  4. Documents We Provide
  5. Transparency & Trustworthiness
    They present as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

It inhibits interleukin-1β (IL-1β) activity, a key cytokine responsible for cartilage degradation and synovial inflammation.

No significant effect; considered safe in metabolic comorbidities.

You can always start with low-dose therapy, take with meals, and maintain adequate hydration.

2–4 weeks depending on order size and documentation.

DMF/CTD dossier, GMP certificate, CoA (3 batches), MSDS, and stability data.

Place an Order or Request a Quote from Salius Pharma

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Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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