Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredient (API)
USP / EP (as applicable)
Duloxetine Hydrochloride
C₁₈H₁₉NOS·HCl
~333.87 g/mol (base); ~395.93 g/mol (HCl)
136434-34-9
(3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride
Thiophene–naphthalene derivative
Antidepressant
| Appearance | White to slightly brownish crystalline powder |
|---|---|
| Solubility | Freely soluble in water; soluble in methanol; slightly soluble in ethanol |
| Melting Point | 176–184°C |
| pH | 5.5–7.0 (1% solution) |
Duloxetine Hydrochloride is a dual serotonin and norepinephrine reuptake inhibitor (SNRI) used extensively in the treatment of depression, anxiety disorders, neuropathic pain, and fibromyalgia. Its high potency and broad therapeutic profile make it a widely demanded molecule in regulated and semi-regulated markets.
It blocks reuptake of serotonin (5-HT) and norepinephrine (NE) at neuronal synapses, which enhances neurotransmitter levels in the CNS → improves mood and modulates pain pathways.
It has minimal affinity for histamine, dopamine, cholinergic, or adrenergic receptors, reducing off-target effects.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
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