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Duloxetine HCl Structure

Product Type

Active Pharmaceutical Ingredient (API)

Grade

USP / EP (as applicable)

Chemical Name

Duloxetine Hydrochloride

Chemical Formula

C₁₈H₁₉NOS·HCl

Molecular Weight

~333.87 g/mol (base); ~395.93 g/mol (HCl)

CAS Number

136434-34-9

IUPAC Name

(3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride

Chemical Class

Thiophene–naphthalene derivative

Therapeutic Class

Antidepressant

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to slightly brownish crystalline powder
Solubility Freely soluble in water; soluble in methanol; slightly soluble in ethanol
Melting Point 176–184°C
pH 5.5–7.0 (1% solution)

Product Description

Duloxetine Hydrochloride is a dual serotonin and norepinephrine reuptake inhibitor (SNRI) used extensively in the treatment of depression, anxiety disorders, neuropathic pain, and fibromyalgia. Its high potency and broad therapeutic profile make it a widely demanded molecule in regulated and semi-regulated markets.

How Duloxetine HCl Works

It blocks reuptake of serotonin (5-HT) and norepinephrine (NE) at neuronal synapses, which enhances neurotransmitter levels in the CNS → improves mood and modulates pain pathways.
It has minimal affinity for histamine, dopamine, cholinergic, or adrenergic receptors, reducing off-target effects.

Use(s)

Adverse Effects

Why choose Salius for Duloxetine HCl?

  1. Regulatory-Grade Manufacturing Standards
    They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release
  2. Enhancing Cost-Effectiveness Through Large Volume API Utilization
    As an exporter and distributor house, Salius aims to deliver high-quality APIs at competitive prices, a key advantage for cost-sensitive markets.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.
  4. Documents We Provide
  5. Transparency & Trustworthiness
    They present as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

Place an Order or Request a Quote from Salius Pharma

Looking to source Duloxetine HCl or other high-quality pharmaceutical products?
We’re here to help.
Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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