API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
BP / EP / JP
C32H39NO2
4-(4-tert-Butylphenyl)-1-[4-(diphenyl methoxy)phenyl]piperidine
90729-43-4
469.65 g/mol
Piperidine derivatives
Anti-Histamine
| Appearance | Off-white crystalline solid |
|---|---|
| Solubility | Freely soluble in ethanol and methanol; slightly soluble in water |
| Melting Point | 110 – 115°C |
| pH (1% aqueous solution) | 5.0 – 7.5 |
Ebastine is a second-generation, non-sedating antihistamine used to treat allergic conditions such as hay fever, allergic rhinitis, and chronic urticaria. It acts by blocking H1 histamine receptors, thereby reducing allergic symptoms like itching, sneezing, and runny nose. Ebastine has minimal sedative effects because it does not significantly cross the blood-brain barrier. It is typically formulated into tablets or syrups and offers long-lasting relief with once-daily dosing.
Ebastine works by selectively blocking peripheral H1 histamine receptors, preventing histamine—a chemical released during allergic reactions—from binding to these receptors. This action alleviates symptoms like sneezing, itching, runny nose, and hives without causing central nervous system depression or drowsiness.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost-competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Ebastine API is the active substance responsible for the antihistamine effects in formulations such as tablets and syrups, used to treat allergies and urticaria.
Ebastine works by selectively blocking peripheral H1 histamine receptors, preventing histamine from binding and triggering allergic symptoms such as itching, sneezing, and swelling.
No. Ebastine is a second-generation antihistamine that does not significantly cross the blood-brain barrier, minimizing sedation compared to older antihistamines.
Ebastine is generally approved for use in children over 12 years old, but dosage and administration should always be guided by a healthcare professional.
Yes. Salius Pharma Pvt. Ltd. exports Ebastine API to several African countries including Nigeria, Kenya, Ghana, South Africa, Tanzania, and Ethiopia, with full WHO-GMP and international regulatory support.
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