Efavirenz

Synonyms

• EFV, DMP 266, (S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

PHYSIOCHEMICAL PROPERTIES

Product Description

Efavirenz is a first-line NNRTI used in combination antiretroviral therapy (ART) for HIV-1 infection. It is widely used globally due to once-daily dosing and high efficacy in viral load suppression.

How Efavirenz Works

Efavirenz works by non-competitively inhibiting HIV-1 reverse transcriptase (RT). It binds to a specific allosteric site on the enzyme, which stops the virus from making DNA. This way, HIV-1 cannot replicate, but it doesn’t affect human DNA polymerases, so our own cells are mostly safe.

Use(s)

• HIV-1 infection in adults and children (>3 months)
• Used in fixed-dose combinations with Tenofovir + Lamivudine/Emtricitabine

Adverse Effects

• CNS effects: dizziness, insomnia, vivid dreams
• Rash and skin reactions
• Hepatotoxicity (rare)
• Fatigue, headache, nausea

Why choose Salius for Efavirenz?

1. Regulatory-Grade Manufacturing Standards
   They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release.
2. Enhancing Cost-Effectiveness Through Large Volume API Utilization
   As an exporter and distributor house, Salius aims to deliver high-quality APIs at competitive prices, a key advantage for cost-sensitive markets.
3. Global Export Experience & Documentation Support
   Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.

4. Transparency & Trustworthiness
   They present as a government-recognized star export house with strong quality and delivery ratings.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Efavirenz
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.