Esomeprazole Sodium

Synonyms

• Nexium, (S)-Esomeprazole Sodium, (S)-5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole sodium salt, Esomeprazole Sodium Hydrate, (S)-Esomeprazole, S-Omeprazole Sodium

PHYSIOCHEMICAL PROPERTIES

Product Description

Esomeprazole Sodium is the sodium salt form of Esomeprazole, the S-enantiomer of Omeprazole. It acts as a selective and irreversible proton pump inhibitor (PPI) by inhibiting the H⁺/K⁺-ATPase enzyme in gastric parietal cells, thereby reducing gastric acid secretion. It is widely used for managing gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger–Ellison syndrome, and for preventing gastric ulcers induced by NSAIDs.

How Esomeprazole Sodium Works

Esomeprazole Sodium selectively inhibits the gastric H⁺/K⁺-ATPase enzyme, which catalyzes the final step of acid production in the stomach. By irreversibly binding to this proton pump, it suppresses both basal and stimulated acid secretion. Being the S-enantiomer of Omeprazole, it provides superior bioavailability, prolonged acid suppression, and more consistent therapeutic outcomes compared to racemic Omeprazole.

Use(s)

• Esomeprazole sodium is used to treat acid-related stomach and esophagus problems like GERD, ulcers, and Zollinger-Ellison syndrome.

Adverse Effects

• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Flatulence
• Dizziness

Why choose Salius for Esomeprazole Sodium?

1. WHO-GMP Certified Manufacturing
   Manufactured in WHO-GMP, ISO 9001:2015, and FDA-audited facilities, ensuring global compliance and exceptional product consistency.
2. Consistent Quality and Reliability
   Salius Pharma ensures stringent process validation, impurity control, and stability testing for pharmaceutical-grade Esomeprazole Sodium.
3. Global Export Experience & Documentation Support
   Comprehensive regulatory documentation including COA, DMF (Open Part), MSDS, TDS, Stability Data, and CTD/ACTD dossiers for global submissions.

4. Focus on Chronic Therapy APIs
   Salius Pharma specializes in chronic therapy APIs, ensuring steady long-term supply and superior technical and regulatory support.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Esomeprazole Sodium
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.