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Etoricoxib Structure

PRODUCT TYPE

API

GRADE

USP/BP

CHEMICAL FORMULA

C18H15ClN2O2S

IUPAC NAME

5-chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine

CAS NO

202409-33-4

MOLECULAR WEIGHT

358.84 g/mol

CHEMICAL CLASS

Pyridines and derivatives

THERAPEUTIC CLASS

NSAID (Selective COX-2 Inhibitor)

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance Off-white crystalline solid
Solubility Soluble in methanol, ethanol, and acetone
Melting Point 139 – 141°C
pH (1% aqueous solution) 6.5 – 7.5

Product Description

Etoricoxib is a selective COX-2 inhibitor and a member of the nonsteroidal anti-inflammatory drug (NSAID) class. It is primarily used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and acute dental pain. By selectively inhibiting the COX-2 enzyme responsible for prostaglandin synthesis, Etoricoxib alleviates inflammation and pain while minimizing gastrointestinal side effects associated with traditional NSAIDs. It is marketed globally under brand names such as Arcoxia and Nucoxia.

How Etoricoxib Works

Etoricoxib acts by selectively inhibiting cyclooxygenase-2 (COX-2), the enzyme responsible for prostaglandin production at inflammation sites. This inhibition decreases prostaglandin levels, which are key mediators of pain, inflammation, and swelling. Because it has minimal activity against COX-1, which maintains gastric mucosal protection and renal blood flow, Etoricoxib offers potent anti-inflammatory effects with a lower risk of gastrointestinal irritation or ulceration compared to non-selective NSAIDs.

Use(s)

Adverse Effects

Why choose Salius for Etoricoxib?

  1. WHO-GMP Certified Manufacturing
    Produced in WHO-GMP, ISO 9001:2015, and FDA-audited facilities, ensuring globally compliant, high-quality Etoricoxib API production.
  2. Consistent Quality and Reliability
    Manufactured under stringent process validation and impurity control procedures, ensuring uniform quality and therapeutic efficacy across batches.
  3. Global Export Experience & Documentation Support
    Backed by extensive regulatory and export documentation such as COA, DMF (Open Part), MSDS, TDS, Stability Data, and CTD/ACTD dossiers for international clients.
  4. Documents We Provide
  5. Focus on Chronic Therapy APIs
    Salius Pharma specializes in APIs for chronic conditions, offering expertise and reliability in long-term therapy APIs like Etoricoxib.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

Etoricoxib is used to treat pain and inflammation in conditions such as arthritis, gout, and acute musculoskeletal pain.

Yes. Prolonged use or use in patients with pre-existing cardiovascular conditions may increase the risk of heart-related side effects. It should be taken under medical supervision.

Allergic reactions are rare but may include rash, itching, swelling, or breathing difficulty. Discontinue use and seek medical help if such symptoms occur.

Yes. Salius Pharma Pvt. Ltd. exports Etoricoxib API to African and Middle Eastern countries including Nigeria, Kenya, UAE, Saudi Arabia, Oman, and others. The company’s export network also covers Latin America, Southeast Asia, and the CIS region.

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