Active Pharmaceutical Ingredients
API
USP/BP
C18H15ClN2O2S
5-chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine
202409-33-4
358.84 g/mol
Pyridines and derivatives
NSAID (Selective COX-2 Inhibitor)
| Appearance | Off-white crystalline solid |
|---|---|
| Solubility | Soluble in methanol, ethanol, and acetone |
| Melting Point | 139 – 141°C |
| pH (1% aqueous solution) | 6.5 – 7.5 |
Etoricoxib is a selective COX-2 inhibitor and a member of the nonsteroidal anti-inflammatory drug (NSAID) class. It is primarily used to relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and acute dental pain. By selectively inhibiting the COX-2 enzyme responsible for prostaglandin synthesis, Etoricoxib alleviates inflammation and pain while minimizing gastrointestinal side effects associated with traditional NSAIDs. It is marketed globally under brand names such as Arcoxia and Nucoxia.
Etoricoxib acts by selectively inhibiting cyclooxygenase-2 (COX-2), the enzyme responsible for prostaglandin production at inflammation sites. This inhibition decreases prostaglandin levels, which are key mediators of pain, inflammation, and swelling. Because it has minimal activity against COX-1, which maintains gastric mucosal protection and renal blood flow, Etoricoxib offers potent anti-inflammatory effects with a lower risk of gastrointestinal irritation or ulceration compared to non-selective NSAIDs.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Etoricoxib is used to treat pain and inflammation in conditions such as arthritis, gout, and acute musculoskeletal pain.
Yes. Prolonged use or use in patients with pre-existing cardiovascular conditions may increase the risk of heart-related side effects. It should be taken under medical supervision.
Allergic reactions are rare but may include rash, itching, swelling, or breathing difficulty. Discontinue use and seek medical help if such symptoms occur.
Yes. Salius Pharma Pvt. Ltd. exports Etoricoxib API to African and Middle Eastern countries including Nigeria, Kenya, UAE, Saudi Arabia, Oman, and others. The company’s export network also covers Latin America, Southeast Asia, and the CIS region.
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