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Gefitinib HCl Structure

PRODUCT TYPE

Active Pharmaceutical Ingredient (API)

GRADE

USP / BP / EP (as applicable)

CHEMICAL NAME

Gefitinib Hydrochloride

CHEMICAL FORMULA

C₂₂H₂₄ClFN₄O₃·HCl

MOLECULAR WEIGHT

484.4 g/mol

CAS NUMBER

184475-35-2

IUPAC NAME

N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine hydrochloride

CHEMICAL CLASS

Quinazoline derivative

THERAPEUTIC CLASS

Antineoplastic agent

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to off-white crystalline powder
Solubility Slightly soluble in water; freely soluble in DMSO, methanol, and ethanol
Melting Point 195–198°C
pH 5.5–7.0

Product Description

Gefitinib hydrochloride is an orally administered, small-molecule tyrosine kinase inhibitor (TKI) used as targeted therapy for specific types of cancer, primarily non-small cell lung cancer (NSCLC). It works by blocking signaling pathways driven by the epidermal growth factor receptor (EGFR) protein, which is often overexpressed or mutated in cancer cells.

How Gefitinib HCl Works

Gefitinib competitively binds to the ATP-binding pocket within the intracellular domain of the EGFR, preventing the receptor from activating downstream signaling pathways that promote cell growth, proliferation, and survival.

Use(s)

Adverse Effects

Why choose Salius for Gefitinib HCl?

  1. Regulatory-Grade Manufacturing Standards
    They maintain stringent WHO GMP standards, with some facilities FDA certified, and follows strict internal QC protocols. Every batch is tested in state-of-the-art labs before release, to ensure consistent quality, safety & efficacy.
  2. Enhancing Cost-Effectiveness Through Large Volume API Utilization
    As an exporter and distributor house, Salius aims to deliver high-quality APIs at competitive prices, a key advantage for cost-sensitive markets.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.
  4. Documents We Provide
  5. Transparency & Trustworthiness
    They present as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

It is used to treat non-small cell lung cancer (NSCLC) by selectively inhibiting the EGFR tyrosine kinase, reducing tumor cell proliferation.

Gefitinib blocks the epidermal growth factor receptor (EGFR) signaling pathway, leading to cell cycle arrest and apoptosis in cancer cells.

Yes, it is supplied as an API compliant with USP, BP, and EP standards, suitable for pharmaceutical formulations.

Store at 2–8°C, protected from light and moisture, to maintain stability and potency.

Packed in double polyethylene bags inside HDPE or fiber drums, shipped via validated cold-chain logistics, ensuring stability during transit.

Place an Order or Request a Quote from Salius Pharma

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Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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