Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredient (API)
USP / BP / EP (as applicable)
Gefitinib Hydrochloride
C₂₂H₂₄ClFN₄O₃·HCl
484.4 g/mol
184475-35-2
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine hydrochloride
Quinazoline derivative
Antineoplastic agent
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Slightly soluble in water; freely soluble in DMSO, methanol, and ethanol |
| Melting Point | 195–198°C |
| pH | 5.5–7.0 |
Gefitinib hydrochloride is an orally administered, small-molecule tyrosine kinase inhibitor (TKI) used as targeted therapy for specific types of cancer, primarily non-small cell lung cancer (NSCLC). It works by blocking signaling pathways driven by the epidermal growth factor receptor (EGFR) protein, which is often overexpressed or mutated in cancer cells.
Gefitinib competitively binds to the ATP-binding pocket within the intracellular domain of the EGFR, preventing the receptor from activating downstream signaling pathways that promote cell growth, proliferation, and survival.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
It is used to treat non-small cell lung cancer (NSCLC) by selectively inhibiting the EGFR tyrosine kinase, reducing tumor cell proliferation.
Gefitinib blocks the epidermal growth factor receptor (EGFR) signaling pathway, leading to cell cycle arrest and apoptosis in cancer cells.
Yes, it is supplied as an API compliant with USP, BP, and EP standards, suitable for pharmaceutical formulations.
Store at 2–8°C, protected from light and moisture, to maintain stability and potency.
Packed in double polyethylene bags inside HDPE or fiber drums, shipped via validated cold-chain logistics, ensuring stability during transit.
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