API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
PN*
C24H34N4O5S
1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea
93479-97-1
490.62 g/mol
Sulfonylurea
Anti Diabetic
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Practically insoluble in water; soluble in dimethyl sulfoxide (DMSO), ethanol, and methanol |
| Melting Point | 206–210 °C |
| pH | - |
Glimepiride is an oral antidiabetic medication belonging to the sulfonylurea class. It is primarily used to manage type 2 diabetes mellitus by stimulating insulin secretion from pancreatic beta cells. Chemically, it is a second-generation sulfonylurea with the molecular formula C₂₃H₃₂N₄O₅S. Glimepiride works by binding to the sulfonylurea receptor on pancreatic beta cells, leading to closure of ATP-sensitive potassium channels, cell depolarization, and subsequent insulin release.
Glimepiride works by stimulating the release of insulin from the pancreatic beta cells. It binds to sulfonylurea receptors on these cells, which leads to the closing of ATP-sensitive potassium channels. This closure causes the cell membrane to depolarize, triggering the opening of voltage-dependent calcium channels. The influx of calcium ions into the cells then promotes the release of insulin stored in secretory vesicles. By increasing insulin secretion, glimepiride helps lower blood glucose levels, making it effective for managing type 2 diabetes. It requires functioning pancreatic beta cells to work and is therefore not used to treat type 1 diabetes.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Glimepiride is used to treat type 2 diabetes mellitus by helping the pancreas release more insulin to lower blood sugar levels.
It is usually taken once daily with breakfast or the first main meal of the day. Always follow your doctor’s instructions.
Yes, hypoglycemia is a common side effect, especially if you skip meals, exercise too much, or combine it with other diabetic medications.
Yes, Salius Pharma Pvt. Ltd. exports Glimepiride API as part of its chronic therapy product range to various international markets, including African and Middle Eastern countries. The company has publicly stated its strategic focus on expanding into regions such as Nigeria, Ghana, Kenya, South Africa, and parts of the Middle East, supported by WHO-GMP and USFDA-certified manufacturing facilities.
Yes, they provide technical support, documentation, and consultation for API use and regulatory compliance.
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