API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
USP/EP
C35H38Cl2N8O4
1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
84625-61-6
705.63 g/mol
Synthetic triazole derivative
Anti-Fungal
| Appearance | White to slightly yellow crystalline powder |
|---|---|
| Solubility | Practically insoluble in water; soluble in methanol, ethanol, and dichloromethane |
| Melting Point | 166–170°C |
| pH | 3.0 |
Itraconazole is a synthetic triazole antifungal agent used to treat a variety of fungal infections, including those affecting the skin, nails, and internal organs. It works by inhibiting fungal cytochrome P450 enzymes, blocking the synthesis of ergosterol, a key component of fungal cell membranes. Itraconazole is available in oral and intravenous formulations and is particularly effective against dermatophytes, yeasts, and systemic fungi such as Aspergillus. Due to its broad-spectrum activity and relatively favorable safety profile, itraconazole is widely used in both superficial and systemic fungal infections.
Itraconazole works by inhibiting the enzyme lanosterol 14α-demethylase, a fungal cytochrome P450 enzyme essential for converting lanosterol to ergosterol, a critical component of the fungal cell membrane. By blocking ergosterol synthesis, itraconazole disrupts the integrity and function of the fungal membrane, leading to impaired cell growth and eventually fungal cell death. This selective inhibition makes itraconazole effective against a wide range of fungal pathogens.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Itraconazole is used to treat fungal infections such as aspergillosis, histoplasmosis, onychomycosis, and skin fungal infections.
It inhibits fungal ergosterol synthesis by blocking the enzyme lanosterol 14α-demethylase, disrupting the fungal cell membrane.
Yes, itraconazole capsules are better absorbed when taken with a full meal; the solution form is best on an empty stomach.
Yes, Salius Pharma Pvt. Ltd. exports Itraconazole API to various countries, including those in Africa and the Middle East. As an ISO 9001:2015 certified company recognized as a Government of India Star Export House, Salius Pharma has a strong presence in international markets. They have a history of exporting Itraconazole Hydrochloride Injection to destinations such as Uganda, Sri Lanka, Thailand, and Colombia.
Yes, Salius Pharma Pvt. Ltd. provides comprehensive technical support and documentation for their Itraconazole API. This includes regulatory dossiers in CTD/eCTD formats, Drug Master Files (DMFs) filed with US FDA and EU authorities, Certificates of Suitability (CEPs) compliant with European Pharmacopoeia standards, and detailed Certificates of Analysis (COAs) for batch-specific testing.
Looking to source Itraconazole or other high-quality pharmaceutical products?
We’re here to help.
Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support,
our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.
The contents of this page and any attachments are intended solely for the designated recipient(s) and may contain confidential and/or privileged information protected by law.
Any patented products are excluded from our offerings in regions where such patents are currently in force.