API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
IP/USP/EP
C15H13NO3.C4H11NO3
(±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, 2-amino-2-(hydroxymethyl)-1,3-propanediol salt
74103-07-4
376.40 g/mol
carboxylic acid derivative
NSAIDs
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Slightly soluble in water; soluble in ethanol and methanol |
| Melting Point | 150–154 °C |
| pH | 4.5–6.0 |
Ketorolac Tromethamine is a potent nonsteroidal anti-inflammatory drug (NSAID) commonly used for short-term management of moderate to severe pain. It works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the production of prostaglandins that cause inflammation, pain, and fever. Available in oral, injectable, nasal, and ophthalmic forms, ketorolac is often used post-surgery, for musculoskeletal pain, and to reduce eye inflammation. Due to potential side effects like gastrointestinal irritation and kidney toxicity, its use is generally limited to short durations under medical supervision.
Ketorolac Tromethamine works by non-selectively inhibiting the cyclooxygenase enzymes COX-1 and COX-2, which are crucial for the conversion of arachidonic acid into prostaglandins. Prostaglandins are substances in the body that promote inflammation, pain, and fever. By blocking their production, ketorolac reduces inflammation and provides effective pain relief. This mechanism makes it especially useful for short-term treatment of moderate to severe pain, particularly after surgery.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
It is used for short-term relief of moderate to severe pain, especially after surgery or for musculoskeletal conditions.
It inhibits COX-1 and COX-2 enzymes, reducing prostaglandin production, which helps relieve pain and inflammation.
No, combining it with other NSAIDs increases the risk of gastrointestinal bleeding and kidney issues.
Yes, Salius Pharma Pvt. Ltd. exports Ketorolac Tromethamine API to countries in Africa and the Middle East. As an ISO 9001:2015 certified and Government of India-recognized Star Export House, the company has a strong international presence, regularly supplying pharmaceutical APIs to regions including the UAE, Saudi Arabia, Nigeria, Kenya, and Egypt.
Yes, Salius Pharma Pvt. Ltd. provides comprehensive technical support and documentation for Ketorolac Tromethamine API. Their offerings include regulatory dossiers in CTD/eCTD format, Drug Master Files (DMFs), Certificates of Suitability (CEPs) aligned with the European Pharmacopoeia, and Certificates of Analysis (COAs) for batch-specific quality assurance. These services are supported by their robust regulatory affairs infrastructure and certified manufacturing facilities adhering to WHO GMP, USFDA, TGA Australia, and UK MHRA standards.
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