API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
API
USP/BP/EP
C8H14N2O2
(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid hemihydrate.
138199-71-0
370.37 g/mol
Fluoroquinolone antibiotic
Anti Biotic (Quinolone)
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Freely soluble in water and methanol; slightly soluble in ethanol |
| Melting Point | 220 °C |
| pH | 5.0-7.0 |
Levofloxacin Hemihydrate is a broad-spectrum fluoroquinolone antibiotic used to treat a wide range of bacterial infections. It is the hemihydrated form of levofloxacin, the active L-isomer of ofloxacin, and offers enhanced antibacterial activity. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and repair, leading to bacterial cell death. Levofloxacin Hemihydrate is commonly used for respiratory tract infections, urinary tract infections, skin infections, and certain gastrointestinal infections, and is available in both oral and injectable forms.
Levofloxacin Hemihydrate works by inhibiting two essential bacterial enzymes: DNA gyrase and topoisomerase IV. These enzymes are critical for DNA replication, repair, and transcription. By blocking their function, levofloxacin prevents bacterial DNA from unwinding and duplicating, ultimately leading to bacterial cell death. This makes it effective against a broad range of Gram-positive and Gram-negative bacteria.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
It is used to treat various bacterial infections, including respiratory, urinary tract, and skin infections.
Levofloxacin Hemihydrate works by inhibiting two key bacterial enzymes—DNA gyrase and topoisomerase IV—which are essential for bacterial DNA replication, repair, and transcription. By blocking these enzymes, Levofloxacin prevents bacteria from multiplying, ultimately leading to their death and the resolution of infection.
Yes, Levofloxacin Hemihydrate can interact with several drugs. It may have reduced absorption when taken with antacids, iron, or zinc supplements. It can also enhance the effects of warfarin, increasing bleeding risk, and may cause heart rhythm issues (QT prolongation) when combined with certain antiarrhythmics. Additionally, using it with NSAIDs or corticosteroids may increase the risk of seizures or tendon rupture. Always consult a doctor before combining it with other medications.
Yes, Salius Pharma Pvt. Ltd. exports Levofloxacin Hemihydrate API to several countries across Africa and the Middle East. While exact destinations and volumes aren’t always disclosed, multiple sources confirm that Salius Pharma is actively targeting these regions and supplying APIs including Levofloxacin Hemihydrate.
Yes, Salius Pharma offers comprehensive technical support and provides all necessary regulatory documentation for Levofloxacin Hemihydrate API, including Drug Master Files (DMF), Certificates of Suitability (CEP), and Common Technical Document (CTD) dossiers. Their support helps facilitate product registration and compliance with international standards. Salius Pharma exports this API to various countries in Africa and the Middle East and maintains certifications from global regulatory authorities, ensuring high-quality standards.
Looking to source Levofloxacin Hemihydrate or other high-quality pharmaceutical products?
We’re here to help.
Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support,
our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.
The contents of this page and any attachments are intended solely for the designated recipient(s) and may contain confidential and/or privileged information protected by law.
Any patented products are excluded from our offerings in regions where such patents are currently in force.