API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredient (API)
USP / BP / EP (as applicable)
Levothyroxine Sodium
C₁₅H₁₀I₄NNaO₄
~798.87 g/mol
25416-65-3
Sodium 2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
Thyroid hormone analogue
Hormone replacement
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Practically insoluble in water; soluble in ethanol, chloroform, and methanol |
| Melting Point | 232–234°C |
| pH | - |
Levothyroxine Sodium is a synthetic form of the thyroid hormone thyroxine (T4) used for hormone replacement therapy in patients with hypothyroidism, thyroid hormone deficiency, or after thyroidectomy. It restores normal thyroid hormone levels, regulating metabolism, growth, and energy production, and is orally active with a predictable pharmacokinetic profile.
Levothyroxine Sodium acts as a thyroid hormone agonist, mimicking the effects of endogenous T4. It is converted to the active hormone T3 in peripheral tissues through deiodination, which then regulates gene expression controlling metabolic rate, protein synthesis, and growth. This activity helps maintain normal energy metabolism and organ function in patients with hypothyroidism.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Yes, Levothyroxine Sodium is tested to ensure endotoxin and pyrogen levels are within pharmacopeial limits, especially for formulations intended for sensitive populations.
Yes, stability studies confirm that Levothyroxine Sodium maintains its thyroid hormone activity under recommended storage conditions, ensuring therapeutic efficacy.
It is primarily used for hypothyroidism, thyroid hormone replacement, goiter management, post-thyroidectomy therapy, and myxedema treatment.
Yes, CoA, MSDS, DMF/CEP, and stability reports are supplied to facilitate international regulatory compliance for LATAM, MENA, Africa, and Asia.
Yes, options such as HDPE drums, nitrogen flushing, fiber drums, and palletized export-ready packing are available for safe delivery in high-humidity or tropical regions.
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