Lopinavir

Synonyms

• ABT-378, Lopinavir USP

PHYSIOCHEMICAL PROPERTIES

Product Description

Lopinavir is a potent HIV-1 protease inhibitor used in combination therapy with Ritonavir to treat HIV infection. It inhibits the HIV-1 protease enzyme, preventing cleavage of viral polyproteins and formation of mature infectious virions. Lopinavir provides high antiviral activity, favorable pharmacokinetics when boosted with Ritonavir, and is widely used in both treatment-naive and experienced patients.

How Lopinavir Works

1. Inhibits HIV-1 protease, preventing cleavage of Gag-Pol polyproteins.
2. Results in production of immature, non-infectious viral particles.
3. Boosted with Ritonavir to increase plasma concentrations via CYP3A4 inhibition.
4. Reduces viral load and improves CD4+ T-cell counts in infected patients.

Use(s)

• Treatment of HIV-1 infection in adults and pediatric patients

Adverse Effects

• Diarrhea
• Nausea
• Headache

Why choose Salius for Lopinavir?

1. Regulatory-Grade Manufacturing Standards
   They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release.
2. Enhancing Cost-Effectiveness Through Large Volume API Utilization
   As an exporter and distributor house, Salius aims to deliver high-quality APIs at competitive prices, a key advantage for cost-sensitive markets.
3. Global Export Experience & Documentation Support
   Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.

4. Transparency & Trustworthiness
   They present as a government-recognized star export house with strong quality and delivery ratings.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Lopinavir
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.