Lumefantrine

Synonyms

• Benflumetol, CGP 56697, Lumefantrinum

PHYSIOCHEMICAL PROPERTIES

Product Description

Lumefantrine is a synthetic arylaminoalcohol antimalarial drug used in combination therapy to treat uncomplicated malaria caused by Plasmodium falciparum. It is most commonly used in fixed-dose combination with artemether (as artemether-lumefantrine, e.g., Coartem).

How Lumefantrine Works

Lumefantrine works by inhibiting the formation of hemozoin, a detoxified form of heme produced by the parasite during hemoglobin digestion. By blocking this process, toxic free heme accumulates, damaging the parasite's membranes and leading to its death. Lumefantrine acts more slowly than artemether but has a longer half-life, helping to eliminate residual parasites and prevent recurrence. Its absorption is significantly enhanced when taken with fatty food.

Use(s)

• Lumefantrine is used in combination with artemether to treat uncomplicated Plasmodium falciparum malaria.

Adverse Effects

• Headache
• Dizziness
• Nausea, vomiting, abdominal pain
• Sleep disturbances (e.g., insomnia)
• Palpitations, QT interval prolongation (rare but serious)

Why choose Salius for Lumefantrine?

1. WHO-GMP Certified Manufacturing
   Salius Pharma produces Lumefantrine in facilities certified by the World Health Organization’s Good Manufacturing Practices (WHO-GMP), ensuring the API meets high-quality, safety, and purity standards required globally.
2. Consistent Quality and Reliability
   They maintain strict quality control protocols to provide consistent, pharmaceutical-grade Lumefantrine. This reliability helps pharmaceutical companies avoid batch failures and regulatory issues.
3. Global Export Experience & Documentation Support
   Salius regularly exports APIs, provides regulatory documents (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.

4. Focus on Chronic Therapy APIs
   Salius specializes in APIs for chronic and infectious diseases, demonstrating expertise in producing reliable compounds like Lumefantrine, often used in long-term treatments and combination therapies.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Lumefantrine
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.