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Metoclopramide Hydrochloride Structure

product_type

API

grade

USP / EP / BP (as required)

chemical_formula

C14H22ClN3O2 · HCl

iupac_name

4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide hydrochloride

cas_no

54143-57-6

molecular_weight

354.30 g/mol

chemical_class

Antiemetic / Prokinetic

Synonyms

PHYSIOCHEMICAL PROPERTIES

appearance White or almost white crystalline powder
solubility Freely soluble in water; Soluble in alcohol; Practically insoluble in methylene chloride
melting_point 179–183°C
ph 4.5 – 6.0 (1% aqueous solution)

Product Description

Metoclopramide Hydrochloride is an antiemetic and gastrointestinal prokinetic API used for nausea, vomiting, delayed gastric emptying, diabetic gastroparesis, and GERD-related complications. It enhances gastric motility and accelerates gastric emptying without affecting gastric secretions.

How Metoclopramide Hydrochloride Works

Primary mechanisms include D2 receptor antagonism in the CTZ (antiemetic), 5-HT4 receptor agonism (increased acetylcholine release leading to enhanced motility and peristalsis), and mild 5-HT3 antagonism for additional antiemetic effect.

Use(s)

Adverse Effects

Why choose Salius for Metoclopramide Hydrochloride?

  1. GMP-Compliant Manufacturing Standards
    Salius Pharma maintains WHO GMP compliance with some FDA-audited facilities and strict in-house QC. Every batch is tested in state-of-the-art laboratories before release.
  2. Cost-Effectiveness
    High-quality Metoclopramide HCl at competitive pricing, suitable for cost-sensitive markets and large-volume supply programs.
  3. Global Export Experience & Documentation Support
    Comprehensive regulatory support including DMF (where applicable), impurity profiles, stability data, and full commercial/export documentation.
  4. Documents We Provide
  5. Transparency & Trustworthiness
    Government-recognized Star Export House with proven quality consistency and on-time delivery performance.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

BP, USP, and EP grades. Each batch undergoes stringent QC to ensure compliance with regulatory standards in regulated and semi-regulated markets.

Yes. COA, MSDS, TDS, stability data, DMF support (where applicable), and commercial documents for customs clearance.

Typically 7–14 business days depending on stock and documentation. Larger orders or PSI requirements may add time.

GI obstruction or perforation, Parkinson’s disease, pheochromocytoma, and history of tardive dyskinesia. Labels in regulated markets must include the required warnings.

Yes. Support for EU, Asia, Africa, Latin America, and Middle East submissions including DMF assistance, impurity profiling, and dossier preparation.

Place an Order or Request a Quote from Salius Pharma

Looking to source Metoclopramide Hydrochloride or other high-quality pharmaceutical products?
We’re here to help.
Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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