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Ondansetron HCl Dihydrate Structure

Product Type

API

Grade

EP/USP

Chemical Formula

C18H19N3O·HCl·2H2O

IUPAC NAME

(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylate

CAS NO

103639-04-9

Molecular Weight

393.9 g/mol

Chemical Class

Selective 5-HT₃ receptor antagonists

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to off-white crystalline powder
Solubility Soluble in water; slightly soluble in methanol
Melting point ~180–183 °C

Product Description

Ondansetron hydrochloride dihydrate prevents nausea and vomiting caused by chemotherapy, radiation, or surgery.

How Ondansetron HCl Dihydrate Works

Ondansetron blocks serotonin 5-HT3 receptors in the brain and GI tract, preventing nausea.

Use(s)

Adverse Effects

Why choose Salius for Ondansetron HCl Dihydrate?

  1. Regulatory-Grade Manufacturing Standards
    They maintain WHO GMP compliance, with some facilities FDA certified, and follow stringent internal QC protocols. Every batch is tested in state-of-the-art labs before release.
  2. Cost-Effectiveness
    As a generic manufacturer and export house, Salius aims to deliver high-quality APIs at competitive prices—a key advantage for cost-sensitive markets.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs, provides regulatory dossiers (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets.
  4. Documents We Provide
  5. Transparency & Trustworthiness
    They present as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015
Export Experience Proven global supplier

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

The dihydrate form includes water molecules within its crystal structure, which can improve the drug’s stability, solubility, and manufacturability compared to the anhydrous form.

Yes, while primarily approved for chemotherapy- and surgery-induced nausea, it is sometimes used off-label for nausea caused by other conditions such as gastroenteritis or pregnancy-related nausea, but only under medical supervision.

Ondansetron blocks 5-HT3 serotonin receptors specifically, preventing nausea signals, while metoclopramide works by blocking dopamine receptors and increasing gastrointestinal motility, making their uses and side effect profiles different.

Salius Pharma supplies Ondansetron HCl Dihydrate as an Active Pharmaceutical Ingredient (API).

To order Ondansetron HCl Dihydrate API, you typically contact a certified pharmaceutical supplier like Salius Pharma. You’ll need to provide details such as desired quantity, intended market, regulatory requirements (e.g., DMF or GMP certificates), and packaging preferences.

Salius Pharma exports Ondansetron HCl Dihydrate to various countries worldwide, including regions such as Asia, Europe, the Middle East, Africa, North America & South America.

Place an Order or Request a Quote from Salius Pharma

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