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Propranolol Hydrochloride Structure

PRODUCT TYPE

API

GRADE

BP / USP

CHEMICAL FORMULA

C16H22ClNO2

IUPAC NAME

(RS)-1-(Isopropylamino)-3-(1-naphthyloxy)propan-2-ol hydrochloride

CAS NO

318-98-9

MOLECULAR WEIGHT

295.81 g/mol

CHEMICAL CLASS

Naphthoxypropanolamine derivative

THERAPEUTIC CLASS

Antihypertensive agent

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to off-white crystalline powder
Solubility Freely soluble in water, methanol, and ethanol; slightly soluble in chloroform; insoluble in ether
Melting Point 163–166°C
pH (1% aqueous solution) 4.5 – 6.5

Product Description

Propranolol Hydrochloride is a non-selective beta-adrenergic receptor blocker used for hypertension, angina pectoris, cardiac arrhythmias, and anxiety-related tachycardia. It remains a cost-effective cornerstone therapy in cardiovascular care.

How Propranolol Hydrochloride Works

Propranolol competitively blocks beta-1 (β1) and beta-2 (β2) adrenergic receptors, reducing heart rate, myocardial contractility, and cardiac output, while suppressing sympathetic nervous system stimulation. This results in lower blood pressure and decreased cardiac workload.

Use(s)

Adverse Effects

Why choose Salius for Propranolol Hydrochloride?

  1. WHO-GMP Certified Manufacturing
    Salius Pharma manufactures Propranolol Hydrochloride in WHO-GMP compliant facilities, ensuring pharmaceutical-grade purity and safety for global markets.
  2. Consistent Quality and Reliability
    Strict in-process and release testing ensure consistent assay, impurity limits, and particle size distribution suitable for all dosage forms.
  3. Global Export Experience & Documentation Support
    Comprehensive documentation including DMF/CTD dossiers, impurity profiles, stability data, and validated analytical methods for international registrations.
  4. Documents We Provide
  5. Focus on Chronic Therapy APIs
    Expertise in chronic therapy APIs ensures long-term supply, regulatory compliance, and formulation support for cardiovascular treatments.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

Manufactured under WHO-GMP and ICH Q7 guidelines with validated synthesis and impurity profiling to meet pharmacopeial standards.

Yes. We offer micronized and non-micronized grades tailored for tablets, capsules, and liquid dosage forms to ensure desired dissolution properties.

Our API is registered and supplied across LATAM, MENA, CIS, and Southeast Asia with CTD/ACTD dossiers and full analytical documentation.

Each batch is packed in HDPE drums with double PE liners, optionally nitrogen-flushed for stability. Shipments follow GDP with COA, MSDS, and TDS enclosed.

Each lot undergoes in-process monitoring, HPLC and GC assays, moisture and stability testing (Zone IVa/IVb) to ensure consistent purity and potency.

Yes. DMF open parts, stability data, and specifications are available prior to commercial agreement for evaluation and registration support.

Place an Order or Request a Quote from Salius Pharma

Looking to source Propranolol Hydrochloride or other high-quality pharmaceutical products?
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Whether you need Active Pharmaceutical Ingredients (APIs), finished formulations, or regulatory support, our team is ready to provide dependable, compliant, and cost-effective solutions tailored to your market needs.

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