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Rizatriptan Benzoate Structure

PRODUCT TYPE

API

GRADE

IP / BP / USP / EP

CHEMICAL FORMULA

C15H19N5• C7H6O2 (benzoate)

IUPAC NAME

N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine benzoate

CAS NO

145202-66-0

MOLECULAR WEIGHT

391.48 g/mol (benzoate salt)

CHEMICAL CLASS

Selective 5-HT1B/1D Receptor Agonist (Anti-migraine Agent)

Synonyms

PHYSIOCHEMICAL PROPERTIES

Appearance White to off-white crystalline powder
Solubility Freely soluble in water; soluble in methanol and ethanol; slightly soluble in organic solvents
Melting Point 180–190°C (approx.)
pH (1% solution) Stable in slightly acidic to neutral conditions

Product Description

Rizatriptan Benzoate is a fast-acting antimigraine API belonging to the triptan class. It is widely used for acute migraine attacks, with or without aura. The benzoate form enhances stability and solubility, making it suitable for tablet and orally disintegrating tablet (ODT) formulations.

How Rizatriptan Benzoate Works

Rizatriptan selectively stimulates 5-HT1B and 5-HT1D receptors, causing cranial blood vessel constriction, inhibition of neuropeptide release, and reduced trigeminal nerve pain signaling. These combined actions provide fast relief from migraine symptoms.

Use(s)

Adverse Effects

Why choose Salius for Rizatriptan Benzoate?

  1. GMP-Compliant Manufacturing Standards
    They maintain stringent WHO GMP standards, with some facilities FDA certified, and follows strict internal QC protocols. Every batch is tested in state-of-the-art labs before release, to ensure consistent quality, safety & efficacy.
  2. Cost-Effectiveness
    As an experienced generic API supplier and export house, Salius aims to deliver high-quality APIs at competitive prices—a key advantage for cost-sensitive and emerging markets.
  3. Global Export Experience & Documentation Support
    Salius regularly exports APIs, provides regulatory dossiers (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets
  4. Documents We Provide
  5. Transparency & Trustworthiness
    They present as a government-recognized star export house with strong quality and delivery ratings.
Attribute Why Salius Pharma Is a Good Choice
Quality Certification WHO GMP, ISO 9001:2015, FDA audited facilities
Affordability & Generic Access Cost competitive generics for global supply
Export Experience Proven track record of supplying globally

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.

FAQs

The formula is C22H25N5O4.

It is a triptan, specifically a serotonin (5-HT) receptor agonist.

It treats acute migraine attacks with or without aura in adults and adolescents.

It binds to 5-HT1B/1D receptors, causing cranial vasoconstriction and inhibiting pro-inflammatory neuropeptide release.

Freely soluble in methanol, soluble in water and ethanol.

High-quality generics at competitive prices for global markets.

Place an Order or Request a Quote from Salius Pharma

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