Sulfasalazine

Synonyms

• Salazosulfapyridine, Azopyridine-sulfonamide, SSZ, Sulfasalazinum

PHYSIOCHEMICAL PROPERTIES

Product Description

Sulfasalazine is an anti-inflammatory and immunomodulatory medication used primarily in the treatment of ulcerative colitis, Crohn’s disease, and rheumatoid arthritis. It consists of two pharmacologically active components—5-aminosalicylic acid (5-ASA) and sulfapyridine—joined by an azo bond that breaks down in the intestine to release both agents. Salius Pharma supplies high-quality Sulfasalazine API as an orange-yellow crystalline powder, compliant with IP, BP, and USP pharmacopeial requirements.

How Sulfasalazine Works

Inside the colon, intestinal bacteria break the azo bond of Sulfasalazine into: 5-ASA (Mesalamine): anti-inflammatory effect on the gut; Sulfapyridine: systemic immunomodulatory activity. Together, these actions reduce inflammation, suppress immune overactivity, and improve gastrointestinal symptoms.

Use(s)

• Ulcerative colitis – induction & maintenance therapy
• Crohn’s disease (colonic involvement)
• Rheumatoid arthritis (as a DMARD)
• Ankylosing spondylitis (adjunct therapy)
• Used for manufacturing coated & uncoated tablets

Adverse Effects

• Nausea, stomach upset
• Loss of appetite
• Headache
• Rash or skin sensitivity
• Reversible sperm count reduction (in some males)
• Rare: blood dyscrasias, liver enzyme elevation

Why choose Salius for Sulfasalazine?

1. GMP-Compliant Manufacturing Standards
   They maintain stringent WHO GMP standards, with some facilities FDA certified, and follows strict internal QC protocols. Every batch is tested in state-of-the-art labs before release, to ensure consistent quality, safety & efficacy.
2. Cost-Effectiveness
   As an experienced generic API supplier and export house, Salius aims to deliver high-quality APIs at competitive prices—a key advantage for cost-sensitive and emerging markets.
3. Global Export Experience & Documentation Support
   Salius regularly exports APIs, provides regulatory dossiers (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets

4. Transparency & Trustworthiness
   They present as a government-recognized star export house with strong quality and delivery ratings.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Sulfasalazine
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.