Tadalafil

Synonyms

• IC-351, Adcirca® API, Cialis® API, Tadalafilum, PDE5 inhibitor compound

PHYSIOCHEMICAL PROPERTIES

Product Description

Tadalafil is a potent, long-acting phosphodiesterase type-5 inhibitor widely used for the treatment of erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH). It enhances smooth muscle relaxation by increasing intracellular cyclic GMP levels, resulting in improved blood flow. Salius Pharma supplies high-purity Tadalafil API meeting IP/BP/USP pharmacopeial requirements.

How Tadalafil Works

Tadalafil works by selectively inhibiting PDE5, an enzyme that breaks down cyclic guanosine monophosphate(cGMP). By allowing cGMP levels to increase, it promotes relaxation of smooth muscle tissues in the corpus cavernosum, prostate, bladder, and pulmonary arteries. This results in: Improved erectile function; Reduced symptoms of BPH; Lower pulmonary arterial pressure. Its long half-life of ~17.5 hours give Tadalafil a duration of action of 24–36 hours, earning it the name "weekend pill" in the ED segment.

Use(s)

• Treatment of erectile dysfunction (ED)
• Benign prostatic hyperplasia (BPH)
• ED + BPH combination therapy
• Pulmonary arterial hypertension (PAH)
• Formulation into tablets, film-coated tablets, and combination drugs

Adverse Effects

• Headache
• Muscle pain
• Nasal congestion
• Back pain
• Flushing
• Indigestion
• Rare: visual disturbances, priapism (prolonged erection)

Why choose Salius for Tadalafil?

1. GMP-Compliant Manufacturing Standards
   They maintain stringent WHO GMP standards, with some facilities FDA certified, and follows strict internal QC protocols. Every batch is tested in state-of-the-art labs before release, to ensure consistent quality, safety & efficacy.
2. Cost-Effectiveness
   As an experienced generic API supplier and export house, Salius aims to deliver high-quality APIs at competitive prices—a key advantage for cost-sensitive and emerging markets.
3. Global Export Experience & Documentation Support
   Salius regularly exports APIs, provides regulatory dossiers (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets

4. Transparency & Trustworthiness
   They present as a government-recognized star export house with strong quality and delivery ratings.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Tadalafil
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.