Tenofovir Alafenamide

Synonyms

• TAF, Tenofovir Alafenamide Fumarate, GS-7340 (research code), Vemlidy® (brand reference)

PHYSIOCHEMICAL PROPERTIES

Product Description

Tenofovir Alafenamide is a novel nucleotide reverse transcriptase inhibitor used for the treatment of HIV-1 infection and chronic hepatitis B. It is a prodrug of tenofovir that delivers higher intracellular concentrations with lower systemic exposure, reducing the risk of renal and bone toxicity compared to Tenofovir Disoproxil Fumarate (TDF).

How Tenofovir Alafenamide Works

TAF is converted inside cells into tenofovir diphosphate. Compete with natural nucleotides to inhibit viral reverse transcriptase. Prevents viral DNA chain elongation, effectively reducing viral replication. Lower plasma tenofovir levels result in improved safety for kidneys and bones.

Use(s)

• HIV-1 infection in adults and adolescents
• Chronic hepatitis B infection
• Combination therapy with other antiretrovirals
• Pre-exposure prophylaxis (PrEP) in select treatment protocols

Adverse Effects

• Nausea
• Headache
• Fatigue
• Mild gastrointestinal disturbances
• Rarely, renal or bone-related effects

Why choose Salius for Tenofovir Alafenamide?

1. GMP-Compliant Manufacturing Standards
   They maintain stringent WHO GMP standards, with some facilities FDA certified, and follows strict internal QC protocols. Every batch is tested in state-of-the-art labs before release, to ensure consistent quality, safety & efficacy.
2. Cost-Effectiveness
   As an experienced generic API supplier and export house, Salius aims to deliver high-quality APIs at competitive prices—a key advantage for cost-sensitive and emerging markets.
3. Global Export Experience & Documentation Support
   Salius regularly exports APIs, provides regulatory dossiers (DMF, impurity profiles), and supports filings for international clients—even in stringent regulated markets

4. Transparency & Trustworthiness
   They present as a government-recognized star export house with strong quality and delivery ratings.

What You Receive in Our Package

When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.

Each Shipment Includes:

Product

• Carefully packed Tenofovir Alafenamide
• Sealed in moisture-resistant, tamper-evident packaging
• Custom drum sizes or blister/bottle formats based on your order

Expected Delivery Time

We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.

Overall Delivery Time:

7 to 21 business days from dispatch, depending on your location.