API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredient (API)
USP / BP / EP (as applicable)
Vinorelbine Tartrate
C₄₅H₅₄N₄O₈·C₄H₆O₆
~1,079.1 g/mol
125317-39-7
(3′R,4′R,5′S,6′S)-5′-Ethyl-6′-(1H-indol-3-yl)-3′,4′,5′,6′-tetrahydro-4′-hydroxy-3′-methoxy-1′H-[2,3′-bipyridine]-2′-yl tartrate (simplified)
Vinca alkaloid
Antineoplastic (Anticancer) Agent
| Appearance | White to off-white crystalline powder |
|---|---|
| Solubility | Freely soluble in water and methanol; slightly soluble in ethanol; practically insoluble in non-polar solvents |
| Melting Point | ~210–215 °C (with decomposition) |
| pH | 3.0 – 5.0 (1% w/v aqueous solution) |
Vinorelbine is derived from the periwinkle plant (Vinca rosea) and is considered a third-generation vinca alkaloid. It was developed to have a more favorable toxicity profile, specifically reduced neurotoxicity, compared to earlier agents like vincristine and vinblastine.
Vinorelbine tartrate primarily exerts its anticancer activity by disrupting the cell cycle during mitosis. It binds to tubulin, the protein subunit responsible for the formation of microtubules, thereby inhibiting the polymerization of tubulin into functional microtubules. Since microtubules are essential for maintaining cell structure and forming the mitotic spindle apparatus, their disruption prevents proper spindle assembly and arrests the cell cycle at metaphase. This mitotic arrest interferes with cell division and ultimately triggers programmed cell death (apoptosis) in rapidly proliferating cancer cells.
| Attribute | Why Salius Pharma Is a Good Choice |
|---|---|
| Quality Certification | WHO GMP, ISO 9001:2015, FDA audited facilities |
| Affordability & Generic Access | Cost competitive generics for global supply |
| Export Experience | Proven track record of supplying globally |
When you order from Salius Pharma, you receive more than just a product — you receive a complete, professionally prepared package that meets international regulatory and quality expectations.
We ensure prompt and reliable shipping worldwide. Delivery times vary depending on destination, order volume, and regulatory requirements.
7 to 21 business days from dispatch, depending on your location.
Vinorelbine Tartrate is mainly used in the treatment of non-small cell lung cancer (NSCLC) and advanced or metastatic breast cancer, either as monotherapy or in combination with other chemotherapeutic agents.
Yes, Vinorelbine Tartrate is manufactured in compliance with USP / EP / BP standards and is supplied to regulated and semi-regulated markets, subject to country-specific regulatory requirements.
Standard export documentation includes Certificate of Analysis (CoA), MSDS, GMP certificate, stability data, and DMF support (where applicable) to facilitate global registrations.
The API is packed in double polyethylene bags placed inside fiber or HDPE drums, stored under controlled conditions, and shipped in compliance with ICH and GDP guidelines to ensure product integrity during transit.
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