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Product Overview

Hydroxypropyl Cellulose (HPC) is a non-ionic, water-soluble cellulose ether derived from cellulose. It serves as a versatile thickener, film-former, binder, and stabilizer in pharmaceutical, cosmetic, food, and industrial applications. Known for its excellent solubility in both water and certain organic solvents, HPC provides good mechanical strength and moisture retention, making it ideal for controlled-release formulations and personal care products.

Product Type: Pharmaceutical Excipient

Chemical Name Hydroxypropyl Cellulose (HPC)
Chemical Formula C₁₂H₂₂O₁₀·(C₆H₇O₂(OH)₃–x(OH)ₓ) (varies with substitution)
CAS Number 9004-64-2
Molecular Weight Varies (typically 10,000 – 1,200,000 Da depending on grade)
Application Role Film-former, thickener, binder, emulsifier, controlled-release agent in pharmaceutical, food, cosmetic, and industrial formulations
Regulatory Compliance USP / NF / EU / JP
Manufacturing Suitability Suitable for oral, topical, and controlled-release pharmaceutical formulations; compatible with tablets, capsules, creams, and coatings
Storage Conditions Store in a tightly sealed container, in a cool, dry place away from heat and direct sunlight.
Certifications GMP, ISO 9001:2008
Availability On-demand production / Global supply capability
HS Code 3912.90.00 – Cellulose ethers, derivatives

Excipient Technical Profile

Appearance White to off-white, free-flowing powder or granules
Bulk Density Typically ranges from 0.35 to 0.55 g/mL
Solubility Soluble in cold or hot water; insoluble in most organic solvents
pH Typically ranges from 6.0 to 8.5 (in 1% aqueous solution)

Typical Applications

Key Benefits

pH stable across a broad range
Non-toxic, non-irritating, and biocompatible
Suitable for controlled drug release in pharmaceuticals
Enhances texture, viscosity, and stability in diverse formulations

Safety Info

Hydroxypropyl cellulose (HPC) is a non-toxic, non-irritating, and biodegradable cellulose derivative widely recognized as safe for use in pharmaceutical, food, cosmetic, and construction applications. It poses minimal risk of sensitization or allergic reactions when handled properly.

⚠️ Key Safety Considerations

  • Avoid inhalation of fine dust during handling to prevent respiratory irritation
  • Use appropriate personal protective equipment (PPE) such as masks and gloves
  • Store in a cool, dry place, away from strong oxidizing agents and moisture
  • Ensure good ventilation in storage and processing areas

Why Choose Salius Pharma?

  • GMP-Compliant Quality: Stringent QC to ensure consistent, premium-grade excipients.
  • Regulatory Support: Comprehensive documentation available.
  • Reliable Supply: Global distribution with timely delivery.
  • Technical Expertise: Dedicated formulation support and customer service.
  • Customized Solutions: Flexible packaging and product grades tailored to your needs.
Documents We Provide

FAQs

HPC is valued for its water solubility, excellent film-forming ability, and thermoplastic properties. It acts as a thickener, binder, emulsifier, and controlled-release agent, making it highly versatile in pharmaceuticals, cosmetics, food, and specialty industrial applications. Its biocompatibility and non-ionic nature ensure broad compatibility and safety.

Salius Pharma manufactures HPC under strict GMP and ISO 9001:2015 standards. Each batch undergoes rigorous quality control including viscosity testing, purity analysis, and microbial limits. Full traceability and compliance with USP, EP, and JP monographs guarantee consistency and regulatory acceptance worldwide.

Salius Pharma offers a broad range of HPC viscosities and substitution levels tailored to the intended application—whether for fast-dissolving tablets, topical gels, or film coatings. Custom packaging sizes and formulations can also be developed in collaboration with clients to optimize performance and processing.

HPC should be stored in cool, dry conditions to prevent moisture absorption and caking. During use, it is best to disperse slowly into water with agitation to avoid lump formation. Protective equipment is recommended to minimize inhalation of fine powder, and dust control measures should be implemented in processing areas.

Salius Pharma supplies HPC in 25 kg moisture-resistant paper bags or fiber drums with inner liners to protect against humidity and contamination. For larger volumes, customized bulk packaging and container shipments are available, ensuring compliance with international transport regulations and maintaining product integrity during transit.

Salius Pharma is recognized as a premium HPC exporter alongside major players like China RuiTai Cellulose Co. and Philippines-based suppliers. Known for its pharmaceutical-grade quality, regulatory documentation, and customer-focused service, Salius offers reliable supply chains and competitive advantages in emerging and established markets globally.

What You Receive with Every Order

At Salius Pharma, we deliver more than just an excipient — we deliver confidence, compliance, and quality. Every shipment is thoughtfully prepared to meet international regulatory standards and your exact specifications.

What’s Included:

✔ Premium Product:
✔ Custom Packaging Options:

Place an Order or Request a Quote from Salius Pharma

Looking to source Hydroxypropyl Cellulose or other high-quality pharmaceutical products?
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Whether you need Active Pharmaceutical Ingredients (APIs), excipients, or regulatory support, our team is ready to provide reliable, compliant, and cost-effective solutions tailored to your market needs.

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