Hydroxypropyl Methylcellulose

Product Overview

Hydroxypropyl Methylcellulose (HPMC) is a semi-synthetic, non-ionic cellulose ether widely used as a thickener, binder, film-former, and stabilizer. Derived from natural cellulose, HPMC is valued for its excellent water solubility, pH stability, and biocompatibility, making it ideal for pharmaceutical, food, cosmetic, and construction applications.

Product Type: Pharmaceutical Excipient

Chemical Name Hydroxypropyl Methylcellulose (HPMC)

Chemical Formula C₁₂H₂₀O₁₀·(C₆H₇O₂(OH)₃–x(OH)ₓ) (varies with substitution)

CAS Number 9004-65-3

Molecular Weight Varies (typically 10,000 – 1,500,000 Da depending on grade)

Application Role Film-former, thickener, binder, emulsifier, controlled-release agent in pharmaceutical, food, cosmetic, and construction formulations

Regulatory Compliance USP / NF / EU / JP

Manufacturing Suitability Suitable for oral, topical, and controlled-release pharmaceutical formulations; compatible with tablets, capsules, creams, and coatings

Storage Conditions Store in a tightly sealed container, in a cool, dry place away from heat and direct sunlight.

Certifications GMP, ISO 9001:2008

Availability On-demand production / Global supply capability

HS Code 3912.90.00 – Cellulose ethers, derivatives

Excipient Technical Profile

Appearance White to off-white, free-flowing powder or granules

Bulk Density Typically ranges from 0.35 to 0.55 g/mL

Solubility Soluble in cold or hot water (hazy colloidal solutions); insoluble in most organic solvents

pH Typically ranges from 6.0 to 8.5 (in 1% aqueous solution)

Typical Applications

Pharmaceutical: Controlled-release tablets, film coatings, binders in tablets and capsules
Food: Thickener, emulsifier, stabilizer in bakery, dairy, and gluten-free products
Cosmetics & Personal Care: Thickener and film-former in lotions, creams, shampoos

Key Benefits

pH stable across a broad range

Non-toxic, non-irritating, and biocompatible

Suitable for controlled drug release in pharmaceuticals

Enhances texture, viscosity, and stability in diverse formulations

Safety Info

⚠️ Key Safety Considerations

Use appropriate personal protective equipment (PPE) such as masks and gloves
Store in a cool, dry place, away from strong oxidizing agents and moisture
Ensure good ventilation in storage and processing areas

Why Choose Salius Pharma?

GMP-Compliant Quality: Stringent QC to ensure consistent, premium-grade excipients.
Regulatory Support: Comprehensive documentation available.
Reliable Supply: Global distribution with timely delivery.
Technical Expertise: Dedicated formulation support and customer service.
Customized Solutions: Flexible packaging and product grades tailored to your needs.

FAQs

HPMC is available in a range of viscosity grades (low, medium, high) depending on the intended application and release profile.

Yes, selected viscosity grades are ideal as matrix formers for controlled-release tablets.

Major exporters include Ashland, Shin-Etsu, DowDuPont, Lotte Fine Chemical, China RuiTai, and in India, Reliance Cellulose, Gujarat Microwax, and Salius Pharma Pvt. Ltd. They supply pharmaceutical-grade HPMC to the US, EU, LATAM, and other regulated markets.

Yes, HPMC is available in various substitution grades with tailored methoxy and hydroxypropyl content to meet specific viscosity, film-forming, and controlled-release requirements.

Yes, Salius Pharma provides DMF, regulatory documentation, and technical support to ensure compliance with global pharmaceutical standards.

What You Receive with Every Order

At Salius Pharma, we deliver more than just an excipient — we deliver confidence, compliance, and quality. Every shipment is thoughtfully prepared to meet international regulatory standards and your exact specifications.

What’s Included:

✔ Premium Product:

High-purity Hydroxypropyl Methylcellulose
Packaged for maximum stability and protection
Moisture-resistant, tamper-evident sealing

✔ Custom Packaging Options:

Tailored drum sizes, blister packs, or bottle formats
Designed to meet your operational needs and dosage requirements

Place an Order or Request a Quote from Salius Pharma

Looking to source Hydroxypropyl Methylcellulose or other high-quality pharmaceutical products?
We’re here to help.
Whether you need Active Pharmaceutical Ingredients (APIs), excipients, or regulatory support, our team is ready to provide reliable, compliant, and cost-effective solutions tailored to your market needs.

Get in Touch

Email: export@saliuspharma.com
Call / WhatsApp: +91 84258 80640 / +91 84258 80643
Landline: +91 22 49700 601 / +91 22 44503 148
Corporate Office: 3104–3106, Plan S Business Park, Nerul MIDC Opp. Dr. D.Y. Patil Stadium, Navi Mumbai – 400706, Maharashtra, India

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