Active Pharmaceutical Ingredients
Donepezil IR (Immediate Release) Pellets are formulated to deliver Donepezil Hydrochloride in a rapid-release form. Donepezil is an acetylcholinesterase inhibitor primarily prescribed for the symptomatic treatment of Alzheimer’s disease and other cognitive disorders. The pellet formulation allows flexible dosage adjustments, improved patient compliance, and potential use in modified oral solid dosage forms like capsules and sachets.
| Component | Function |
|---|---|
| Donepezil Hydrochloride | Active Pharmaceutical Ingredient (API) |
| Sugar Spheres / MCC Spheres | Inert core or starter pellets |
| Hydroxypropyl Methylcellulose (HPMC) | Binder / Film former during layering |
| Talc / Colloidal Silicon Dioxide | Anti-adherent / Glidant |
| Polyvinylpyrrolidone (PVP) or equivalent | Binder for uniform layering |
| PEG 6000 / Triethyl Citrate | Plasticizer for film coating |
| Purified Water | Solvent (removed after processing) |
Outsourcing pellets through a trusted partner like Salius Pharma can be a strategic decision to save both time and resources, without compromising on quality or compliance. Instead, partnering with Salius Pharma—a leading distributor aligned with USFDA-approved and WHO-GMP-certified manufacturers in India—allows you to leverage high-quality products, seamless logistics, and professional support under one roof.
We ensure prompt and reliable shipping worldwide. Delivery times may vary depending on destination, order volume, and regulatory requirements.
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They are primarily used in the treatment of Alzheimer’s disease to enhance cognitive function by inhibiting acetylcholinesterase.
While capsule filling is most common, Donepezil IR Pellets can also be compressed into tablets or packed into sachets.
They should be stored in an airtight container, away from direct sunlight, heat, and moisture to maintain drug stability.
Yes, they are manufactured under cGMP guidelines and comply with pharmacopeial standards (USP/EP/JP), making them suitable for global markets.