API's
Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients
Nifedipine SR Pellets are specially designed for sustained oral delivery of Nifedipine, a dihydropyridine calcium channel blocker widely used in the treatment of hypertension, angina pectoris, and other cardiovascular conditions. Utilizing advanced pelletization technology and polymer-based controlled-release coatings, these pellets ensure gradual drug release over a 12–24-hour period, resulting in stable plasma concentrations, reduced side effects, and improved patient compliance through once-daily dosing.
| Component | Function |
|---|---|
| Nifedipine HCl | Active Pharmaceutical Ingredient (API) |
| Sugar Spheres / MCC Pellets | Inert core |
| Hypromellose (HPMC) | Binder |
| Ethyl Cellulose | Sustained-release polymer |
| Starch | Water-insoluble excipient for pellet matrix |
| Eudragit RS / RL | Functional polymer |
| Polyvinylpyrrolidone (PVP K30) | Binder |
| Triethyl Citrate / Triacetin / Diethyl Phthalate | Plasticizer |
| Talc | Anti-adherent |
| Colloidal Silicon Dioxide | Glidant and anti-adherent |
| Purified Water / Isopropyl Alcohol | Solvent used for layering and coating |
| PEG (MW 4,000–20,000) | Dispersants for coating suspension |
| Tween-80 | Emulsifiers for coating suspension |
Salius Pharma offers Nifedipine HCl Pellets manufactured in USFDA-approved, WHO-GMP, and ISO-certified facilities in India. Our products are developed using cutting-edge pelletization and controlled-release coating techniques, ensuring consistent quality, enhanced bioavailability, and targeted release profiles.
We provide tailored strengths and pellet sizes to meet specific formulation objectives for once- or twice-daily cardiovascular therapies. With extensive experience in global exports and regulatory support, our pellets are ready for integration into finished dosage forms in both regulated and semi-regulated markets.
We ensure prompt and reliable shipping worldwide. Delivery times may vary depending on destination, order volume, and regulatory requirements.
Looking to source Nifedipine SR Pellets or other high-quality pharmaceutical pellet formulations?
Whether you need Active Pharmaceutical Ingredients (APIs), excipients, or regulatory support, our team is ready to provide reliable, compliant, and cost-effective solutions tailored to your market needs.
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Any patented products are excluded from our offerings in regions where such patents are currently in force.
Nifedipine HCl Pellets are multiparticulate oral dosage forms designed for controlled or sustained release, helping maintain consistent therapeutic levels for cardiovascular conditions like hypertension and angina.
Yes. They are suitable for direct compression into tablets or capsule filling, providing manufacturers flexibility in oral dosage form development while maintaining uniformity and consistent drug release.
Salius Pharma offers custom drug loads, pellet sizes, coating materials, and release profiles to meet specific formulation, regulatory, and market requirements.
All batches are produced under GMP standards, tested for content uniformity, dissolution, and stability, and shipped with complete regulatory documentation (CoA, MSDS, stability reports) for safe international distribution.